Am­pio shares are rout­ed (again) as its PhI­II do-over for os­teoarthri­tis flops

Last April lit­tle Am­pio Phar­ma­ceu­ti­cals $AMPE strug­gled to put the best face on the Phase III fail­ure of its os­teoarthri­tis drug Am­pi­on. The dread place­bo ef­fect scut­tled the study, ex­ecs protest­ed, as its stock was crushed in the in­stant rout.

By last fall, though, the En­gle­wood, CO-based biotech came back with a new Phase III, sig­nif­i­cant­ly de-risked, they said, based on pri­or re­sults and a spe­cial pro­to­col as­sess­ment with the FDA that put suc­cess with­in their grasp.

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