As­traZeneca records an­oth­er R&D set­back, trig­ger­ing a melt­down at Synair­gen

More than two years af­ter As­traZeneca in-li­censed Synair­gen’s lead drug, the phar­ma gi­ant $AZN has had to scrap a Phase IIa study of the in­haled in­ter­fer­on be­ta for asth­ma. And the British biotech’s stock quick­ly tanked on the lat­est sna­fu to af­flict As­traZeneca.

The biotech said ear­ly Wednes­day that As­traZeneca opt­ed to halt the study ear­ly af­ter de­ter­min­ing that an over­all low num­ber of ex­ac­er­ba­tions among the asth­ma pa­tients re­cruit­ed would make it dif­fi­cult to see if they could ac­tu­al­ly hit the pri­ma­ry end­point that had been laid out. But in­ves­ti­ga­tors still plan to sift through the da­ta to see how the drug did on sec­ondary goals.

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