No­vavax shares are rout­ed af­ter its big PhI­II RSV vac­cine tri­al flops

No­vavax $NVAX says that its big Phase III study of its RSV vac­cine failed bad­ly among old­er sub­jects, flop­ping on the pri­ma­ry as well as sec­ondary out­comes and leav­ing the biotech strug­gling to ex­plain how it fell short here.

The com­pa­ny re­cruit­ed 11,856 peo­ple over the age of 60 for this study, look­ing for clear ev­i­dence to sup­port a claim that the vac­cine could sig­nif­i­cant­ly pre­vent RSV-as­so­ci­at­ed low­er res­pi­ra­to­ry tract dis­ease – the pri­ma­ry goal – or at least in­ci­dents of all symp­to­matic res­pi­ra­to­ry dis­ease due to RSV. It didn’t work.

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