J&J hands Tra­con two drugs, out­lines buy­back; Zymeworks does a cross-li­cens­ing deal with Dai­ichi Sankyo

Typ­i­cal­ly we see Big Phar­mas in-li­cens­ing ex­per­i­men­tal drugs from small biotechs. But in a re­verse of those roles, San Diego-based Tra­con Phar­ma­ceu­ti­cals bagged a cou­ple of pro­grams from phar­ma gi­ant J&J. And J&J is al­so in­vest­ing $5 mil­lion in an eq­ui­ty stake for its new part­ner. This is a two-way deal, though, as J&J al­so out­lined some spe­cif­ic deal terms if it wants these drugs back. J&J agreed to pay Tra­con $45 mil­lion up­front and up to $137.5 mil­lion in mile­stones to re­trieve JNJ-63576253, a prostate can­cer ther­a­py. And JNJ-64290694 for hema­to­log­ic ma­lig­nan­cies can be roped back af­ter ne­go­ti­a­tions. If Tra­con keeps that drug, it will be on the hook for up to $60 mil­lion in mile­stones. Ku­dos on the in­no­v­a­tive deal struc­ture.

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