Mer­ck part­ners up on T-cell tech plat­form in $374M au­toim­mune deal; Turn­stone taps BMS vet Mike Burgess for top R&D role

→ Back at the be­gin­ning of the year, the team at Cue Bio­phar­ma brought its A round up to $26 mil­lion af­ter build­ing a plat­form tech that re­volves around its work or­ches­trat­ing T cell re­spons­es. Any­one fa­mil­iar with the field will rec­og­nize an im­por­tant strat­e­gy here that in­volves amp­ing up an im­mune re­sponse (can­cer, for one) or dis­man­tling it (au­toim­mune dis­eases). To­day, gi­ant Mer­ck — which has an R&D team that is built to progress its PD-1 drug Keytru­da — has cho­sen to part­ner up with the new-wave Cam­bridge, MA com­pa­ny. In­ter­est­ing­ly, Mer­ck’s in­ter­est is on the au­toim­mune side of things. We have no idea what the up­front is — Mer­ck likes to be qui­et about the cash it spends — but R&D chief Roger Perl­mut­ter has en­gi­neered a string of small li­cens­ing deals and ac­qui­si­tions to aug­ment their pipeline op­er­a­tions. The mile­stones to­tal up to $374 mil­lion. This is all we hear about the fo­cus: “The mul­ti-year col­lab­o­ra­tion will en­com­pass mul­ti­ple dis­ease tar­gets across cer­tain pri­ma­ry dis­ease in­di­ca­tion ar­eas.” Now you know.

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