Momenta hit with a setback as pancreatic cancer drug flops in PhII
Momenta Pharmaceuticals has been hit with a setback. The Cambridge, MA-based biotech says that its Phase II study matching the experimental necuparanib with Abraxane and gemcitabine failed to make an appreciable dent in metastatic pancreatic cancer.
At the halfway point of the study, with 57 deaths, the data monitoring committee decided that they weren’t seeing any evidence that the drug was making a significant difference for patients. Now they’re shutting the study down and unblinding the data to see what the next best step will be for the patients who are left.
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