Troubled Aveo hit with another setback as investigators shutter PhII
Aveo Oncology may be under new management, but it’s still afflicted by a long-running pattern of trouble in the clinic. Usually, that trouble has been focused on its lead drug tivozanib. This time, though, the setback is for its number two drug in the clinic.
In a filing with the SEC Monday morning, the biotech $AVEO says that it was forced to discontinue a mid-stage study for ficlatuzumab due to a high discontinuation rate among a group of patients in the drug arm. The drug is a hepatocyte growth factor (HGF) inhibitory antibody.
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