5 years later, CAR-T pioneer Kymriah offers jaw-dropping evidence of durable remissions — even as it still proves a tough sell
Just a couple of weeks after Bristol Myers Squibb finally won an FDA OK for liso-cel, investigators at Penn posted a 5-year update on a small group of patients suffering from non-Hodgkin lymphoma who were treated with Novartis’ pioneering CAR-T Kymriah. And it’s impressive.
For these advanced, treatment-resistant NHL patients, 46% had achieved a complete remission, with 31% marking progression free survival at the 5-year point. And researchers determined that durable success here hinges on patients’ response one year into the treatment. This is the longest stretch yet reported on for these patients.
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