Ali Raza Khaki (Stanford)

95% of new on­col­o­gy drugs ap­proved in US be­fore Eu­rope in past decade, study finds

Ali Raza Kha­ki is a blad­der can­cer doc­tor at Stan­ford. He’s seen five im­mune check­point in­hibitors ap­proved as a sec­ond line of treat­ment, but he re­al­ly on­ly us­es one for that in­di­ca­tion — pem­brolizum­ab, mar­ket­ed as Keytru­da, since it’s the on­ly one with ran­dom­ized con­trolled tri­al da­ta.

Two of the oth­er in­hibitors, As­traZeneca’s Imfinzi and Roche’s Tecen­triq, have since had their ac­cel­er­at­ed ap­provals for blad­der can­cer pulled by the FDA (or rather, the Big Phar­mas ‘vol­un­tar­i­ly with­drew’ them).

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