Reshma Kewalramani. Vertex

A deal-hun­gry Ver­tex ush­ers in three more gene edit­ing pro­grams as it clos­es out har­bin­ger CRISPR deal

Back in 2015, Ver­tex made a splash in the nascent CRISPR gene edit­ing world by wa­ger­ing $105 mil­lion to part­ner with one of its pi­o­neers — then-pri­vate start­up CRISPR Ther­a­peu­tics — to gen­er­ate up to six new treat­ments for ge­net­ic dis­eases.

Fast for­ward four years, the duo has ac­com­plished the his­toric feat of dos­ing their ex vi­vo ther­a­py, CTX001, in pa­tients with be­ta tha­lassemia, and Ver­tex has clear­ly sig­naled its in­tent on go­ing big­ger in­to gene edit­ing tech. As they wrap up the re­search part of their col­lab­o­ra­tion, the big biotech is tap­ping three more CRISPR pro­grams for its pipeline, which has bal­looned in re­cent weeks with new drugs in­tro­duced from new pacts.

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