A new RNA part­ner­ship hunts rare epilep­sies; Ab­b­Vie and I-Mab tack­le CD47

Zo­genix is get­ting a new part­ner as it looks to tack­le rare child­hood seizures.

The Cal­i­for­nia-based biotech, which de­vel­oped and pro­duces the seizure drug Fin­tepla, is team­ing with Tre­vard Bio­sciences to de­vel­op RNA-based gene ther­a­pies for Dravet syn­drome and oth­er ge­net­ic epilep­sies.

Spun out of MIT and ad­vised by David Liu and Bob Langer, Tre­vard is try­ing to use tran­scrip­tion­al RNA to in­crease the ex­pres­sion of healthy copies of the gene be­hind Dravet’s syn­drome in pa­tients and de­crease the ex­pres­sion of the faulty copy.

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