Miguel Forte, Bone Therapeutics

A tiny biotech racks up an­oth­er PhI­II fail, crip­pling its share price

Close to 3 years af­ter tiny Bel­gian biotech Bone Ther­a­peu­tics crashed on the Phase III fail­ure of its treat­ment for os­teonecro­sis, it’s back with an­oth­er piv­otal flop.

This time the Phase III fail­ure is for their “vis­co­sup­ple­ment” JTA-004 for os­teoarthri­tis, which went down on the pri­ma­ry and both sec­ondary end­points. The pri­ma­ry end­point was a re­duc­tion in knee pain at 3 months com­pared against a place­bo.

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