Alex­ion touts new PhI­II da­ta of Soliris suc­ces­sor as planned As­traZeneca takeover looms

A lit­tle less than a week be­fore As­traZeneca’s takeover of Alex­ion is ex­pect­ed to be com­plet­ed, the rare dis­ease biotech  of­fered up a cut of da­ta for its Soliris suc­ces­sor.

In a Phase III study for Ul­tomiris look­ing at adults with gen­er­al­ized myas­the­nia gravis, the drug met its pri­ma­ry end­point of sig­nif­i­cant­ly im­prov­ing scores on a pa­tient-re­port­ed as­sess­ment com­pared to place­bo af­ter 26 weeks, Alex­ion an­nounced Thurs­day af­ter­noon. Alex­ion hopes the topline re­sults rep­re­sent what could be Ul­tomiris’ third ap­proval, af­ter it notched OKs for a rare blood dis­or­der called PNH and an ul­tra-rare chron­ic dis­ease that dam­ages the kid­neys.

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