Ar­cus to raise $99M IPO; Van­da wants mar­ket­ing ap­proval for jet lag

→ Clin­i­cal-stage can­cer im­munother­a­py mak­er Ar­cus Bio­sciences has set out to raise $99 mil­lion in an IPO, of­fer­ing 7.1 mil­lion shares at a price range of $13 to $15 per share. At the mid­point of that range, the com­pa­ny would get a mar­ket val­ue of $600 mil­lion, ac­cord­ing to Re­nais­sance Cap­i­tal. The com­pa­ny plans to list on the NYSE un­der the tick­er $RCUS. The IPO is ex­pect­ed to price on March 12. Based in Hay­ward, Cal­i­for­nia, Ar­cus’s port­fo­lio in­cludes AB928, a dual an­tag­o­nist of adeno­sine re­cep­tors; AB122, a mon­o­clon­al an­ti­body that blocks PD-1; AB680, an in­hibitor of CD73 re­spon­si­ble for the ex­tra­cel­lu­lar pro­duc­tion of adeno­sine with­in the tu­mor mi­cro-en­vi­ron­ment; and AB154, a mon­o­clon­al an­ti­body that blocks a nov­el im­mune check­point.

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