Jeff Jones, Cullinan Oncology CMO

#AS­CO22: With me­di­an dura­bil­i­ty da­ta, Cul­li­nan aims to 'dis­tin­guish it­self' from Takeda's Exkiv­i­ty and J&J's Ry­bre­vant in ex­on 20 NSCLC

CHICA­GO — In its “first time on a big­ger stage” at this week­end’s AS­CO con­fer­ence, Cul­li­nan On­col­o­gy thinks it has the da­ta to “dis­tin­guish it­self” from the on­ly oth­er ap­proved drugs for EGFR ex­on 20 in­ser­tion mu­ta­tions, which are found in about 2% to 3% of pa­tients with non-small cell lung can­cer, CMO Jeff Jones tells End­points News.

Those are Take­da’s Exkiv­i­ty and John­son & John­son’s Ry­bre­vant, both green­lit last year. While those Big Phar­mas might have crossed the fin­ish line first, Cul­li­nan says its drug is bet­ter in terms of dura­bil­i­ty of re­sponse, and that’s like­ly at­trib­uted to a rel­a­tive­ly bet­ter tol­er­a­bil­i­ty pro­file, Jones said.

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.