As­traZeneca says mon­o­clon­al an­ti­body com­bo is 77% ef­fec­tive at pre­vent­ing Covid-19

Af­ter hit­ting just about every pot­hole with its Covid-19 vac­cine roll­out, As­traZeneca has some good news to share for an­oth­er pan­dem­ic-re­lat­ed pro­gram: Its mon­o­clon­al an­ti­body com­bo, AZD7442, proved ef­fec­tive at pre­vent­ing symp­to­matic Covid-19 in a Phase III study.

AZD7442 re­duced the risk of symp­to­matic Covid-19 by 77%, based on a pre­lim­i­nary group of cas­es in a large, glob­al Phase III tri­al, ac­cord­ing to the British phar­ma. The study, dubbed PROVENT, en­rolled near­ly 5,200 vol­un­teers across the US, UK, Spain, France and Bel­gium, 75% of whom had co­mor­bidi­ties or con­di­tions that would cause a re­duced im­mune re­sponse to vac­ci­na­tion.

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