As­traZeneca signs com­pu­ta­tion­al drug dis­cov­ery col­lab­o­ra­tion; J&J-part­nered Fate cleared for the clin­ic

As­traZeneca has picked out its lat­est com­pu­ta­tion­al part­ner from Toron­to, tap­ping Pro­tein­Qure to ap­ply its struc­ture-based de­sign plat­form for the cre­ation of pep­tide ther­a­peu­tic li­braries. The phar­ma gi­ant is re­spon­si­ble for ex­per­i­men­tal val­i­da­tion of the leads gen­er­at­ed from the col­lab­o­ra­tion.

→ Three months af­ter J&J cast a bright spot­light on Fate’s pi­o­neer­ing stem cell tech­nol­o­gy, the biotech has se­cured clear­ance from the FDA to be­gin a first-in-hu­man study. The Phase I will test an off-the-shelf CAR-T ther­a­py tar­get­ing CD19+ tu­mors.

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