As­traZeneca's clot-fight­er Bril­in­ta shows promise in di­a­bet­ics with heart dis­ease in big study

As Pas­cal So­ri­ot pol­ish­es the rough edges of his R&D shop with­in As­traZeneca, the British drug­mak­er re­port­ed some en­cour­ag­ing news that could help it ex­pand the use of its clot-fight­er Bril­in­ta, once tout­ed as a $3.5 bil­lion-a-year treat­ment.

The drug, which gen­er­at­ed rough­ly $1.3 bil­lion last year and was one of As­traZeneca’s top ten med­i­cines, was shown in 2017 — as part of a sub-group analy­sis — to in­duce a sub­stan­tial 29% re­duc­tion in the risk of car­dio­vas­cu­lar death in pa­tients who had pre­vi­ous­ly suf­fered a heart at­tack and who con­tin­ued to take the treat­ment as well as as­pirin past the first full year of ther­a­py.

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