Avi­ra­gen shares plunge as RSV an­tivi­ral flunks a small PhI­Ia study

The an­tivi­ral biotech Avi­ra­gen $AVIR says that its ex­per­i­men­tal RSV ther­a­py BTA585 flunked a small Phase IIa study in vol­un­teers who had been in­tranasal­ly in­fect­ed with the virus.

On­ly about 20 pa­tients were re­cruit­ed for the study. Di­vid­ed in­to three co­horts, two re­ceived dif­fer­ent dos­es of BTA585 and the third was treat­ed with a place­bo. The pri­ma­ry end­point was vi­ral load with some sec­ondary end­points on the sever­i­ty of RSV dis­ease as mea­sured by 10 RSV-re­lat­ed clin­i­cal symp­toms and mu­cus weight.

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