Bain, RA back In­flaRx’s $55M round af­ter ear­ly study pro­duces promis­ing re­sults

A lit­tle more than a month ago, Ger­many’s In­flaRx rolled out some promis­ing proof-of-con­cept da­ta from a small Phase IIa study of its lead drug, a com­ple­ment fac­tor C5a mon­o­clon­al an­ti­body tar­get­ing a rare skin dis­ease called Hidradeni­tis Sup­pu­ra­ti­va.

Ac­cord­ing to re­searchers, an im­pres­sive 10 of the 12 pa­tients in the study — which in­clud­ed 9 drug-re­sis­tant pa­tients — achieved a clin­i­cal re­sponse, with a sig­nif­i­cant 50% or greater re­duc­tion in in­flam­ma­to­ry le­sion count (ab­scess­es and in­flam­ma­to­ry nod­ules) and no in­crease in ab­scess­es or drain­ing fis­tu­las when com­pared with base­line.

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