Bay­er, J&J wrap pos­i­tive PhI­II car­dio study for Xarel­to ear­ly, look­ing to beef up its mar­ket

Back in the fall of 2012, its sights set on build­ing a block­buster flag­ship drug out of its an­ti­co­ag­u­lant Xarel­to, Bay­er and its part­ners at J&J set out to do a mas­sive study to see if the drug could help pre­vent ma­jor car­dio­vas­cu­lar events like stroke, my­ocar­dial in­farc­tion and death in high risk pa­tients with coro­nary artery dis­ease or pe­riph­er­al artery dis­ease.

To­day, a lit­tle more than 4 years and 27,000-plus pa­tients lat­er, in­ves­ti­ga­tors say that they hit the pri­ma­ry end­point well ahead of sched­ule. Now they’re end­ing the tri­al ear­ly and launch­ing an ex­ten­sion study where they will con­tin­ue to dose pa­tients.

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