Bial ac­cused of neg­li­gence in lethal drug tri­al — Na­ture

David Webb, pres­i­dent of the British Phar­ma­co­log­i­cal So­ci­ety, says that new rev­e­la­tions at a re­cent con­fer­ence proved that the in­ves­ti­ga­tors from Por­tuguese biotech Bial were “fly­ing blind” when they start­ed a tri­al which left one pa­tient dead and four oth­ers with lin­ger­ing neu­ro­log­i­cal dam­age.

The rev­e­la­tion, re­ports Na­ture, is that Bial over­looked the phar­ma­co­dy­nam­ic da­ta on a low dose of BIA 10-2474 be­fore tak­ing the dose high­er.

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.

SIGN UP LOG IN BECOME A PREMIUM SUBSCRIBER