Michel Vounatsos (Credit: World Economic Forum/Ciaran McCrickard)

Bio­gen bets $60M up­front that a new an­ti­sense can­di­date from Io­n­is can one-up Spin­raza

As Bio­gen stares down an im­pend­ing patent cliff for its spinal mus­cu­lar at­ro­phy block­buster Spin­raza, it’s bet­ting $60 mil­lion that a new an­ti­sense oligonu­cleotide from Io­n­is will help keep the com­pa­ny’s lead in that space.

Build­ing on a years­long re­la­tion­ship with Io­n­is, Bio­gen plumped down $60 mil­lion just be­fore the new year to se­cure com­mer­cial and de­vel­op­ment rights to BI­IB115, a pre­clin­i­cal SMA drug look­ing to one-up Spin­raza, the com­pa­nies an­nounced Tues­day. The lat­ter raked in just over $2 bil­lion last year (a slight de­crease from the year be­fore) but faces a patent ex­pi­ra­tion as ear­ly as 2023.

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