Harold Bernstein, BioMarin CMO

Bio­Marin re­cruits Ver­tex's trans­la­tion­al chief to head up clin­i­cal tri­al ops

Af­ter spend­ing the last 4 years push­ing trans­la­tion­al re­search at the deep sci­ence-fo­cused Ver­tex, Harold Bern­stein is mak­ing the leap in­to the clin­i­cal world, plant­i­ng both feet in drug de­vel­op­ment as Bio­Marin’s new SVP and chief med­ical of­fi­cer.

Bern­stein’s new role puts him in charge of clin­i­cal de­vel­op­ment at the San Fran­cis­co-based biotech where things haven’t al­ways gone smooth­ly. Most no­tably, Bio­Marin’s of­ten-tout­ed he­mo­phil­ia A gene ther­a­py has dis­played a ten­den­cy to wan­ing ef­fi­ca­cy, rais­ing doubts that prompt­ed the FDA to im­pose a lengthy de­lay on the com­pa­ny be­fore any mar­ket­ing de­ci­sion.

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