Boom­ing rare dis­ease play­er Shire adding a trendy new R&D hub in Kendall Square for 1,000-plus

Shire CEO Flem­ming Orn­skov has al­ready made it clear that he in­tends to make the com­pa­ny a lead­ing force in rare dis­ease drug de­vel­op­ment and mar­ket­ing. Now he’s mov­ing to al­so make it one of the most vis­i­ble play­ers in the field.

Orn­skov has inked a lease for the 343,000-square-foot build­ing at 500 Kendall Street, right next to the 650 Kendall Street ad­dress it al­ready owns. The plan is to turn Gen­zyme’s old fa­cil­i­ty in­to a rare dis­ease in­no­va­tion hub with more than 1,000 staffers. And it plans to move in cross-dis­ci­pli­nary teams in­volved in re­search, clin­i­cal de­vel­op­ment, med­ical af­fairs, busi­ness de­vel­op­ment and more.

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