Harpreet Singh, Immatics CEO (Credit: Allogeneic Cell Therapies Summit)

Bris­tol My­ers antes up on a $920M part­ner­ship play for a next-gen — but ear­ly stage — bis­pe­cif­ic with a cou­ple of unique twists

Just a few weeks af­ter of­fer­ing a pos­i­tive read­out on its first ear­ly clin­i­cal-stage of­fer­ing, the transat­lantic biotech Im­mat­ics is back with news that the re­search crowd around Ru­pert Vessey at Bris­tol My­ers Squibb has an­ted up $150 mil­lion in cash to get on at the ground floor with one of their still-pre­clin­i­cal ef­forts.

This time the news is cen­tered on IMA401, Im­mat­ics’ most ad­vanced bis­pe­cif­ic, which us­es one binder to latch on to MAGEA4/8 while an­oth­er is used to whip up T cell ac­tiv­i­ty against tu­mor cells where that’s a com­mon anti­gen. For now, that’s still a pre­clin­i­cal ef­fort, with the first hu­man tri­al set to launch in the first half of next year.

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