Can a new pro­tein bring RNA drugs where they can't reach? J&J vet Sue Dil­lon's Io­n­is-part­nered biotech gets $88M to prove yes

Sue Dil­lon re­mem­bers the un­cer­tain­ty when she first left J&J to start her own biotech around a new kind of mol­e­cules called cen­tyrins.

J&J had al­ready li­censed the tech, which was de­vel­oped by her co-founder Karyn O’Neil at the phar­ma gi­ant’s Cen­tyrex unit, to two com­pa­nies for use in CAR-T and ra­dio­phar­ma­ceu­ti­cals. But Aro Bio­ther­a­peu­tics want­ed to ap­ply it to what was still a nascent area: RNA med­i­cines, en­com­pass­ing both an­ti­sense oligonu­cleotides and siR­NA ther­a­pies.

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