Cel­lec­tis preps for ground­break­ing US tri­als for an off-the-shelf CAR-T ther­a­py

Cel­lec­tis is ramp­ing up the first-ever US tri­al launch­es for an off-the-shelf CAR-T ther­a­py.

The Paris-based biotech $CLLS, which has a siz­able R&D group in Man­hat­tan, says the FDA has signed off on their IND for a Phase I study of UCART123 in acute myeloid leukemia and blas­tic plas­ma­cy­toid den­drit­ic cell neo­plasm.

The plan now is to get start­ed in the next few months, wrap up their ear­ly-stage work in ear­ly 2018 and then launch what they hope will be a reg­is­tra­tional Phase II tri­al in mid-2018 — pro­vid­ed the FDA signs off, Dr. Loan Hoang-Sayag, Cel­lec­tis’ chief med­ical of­fi­cer, tells End­points News via email.

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.

SIGN UP LOG IN BECOME A PREMIUM SUBSCRIBER