Cem­pra slash­es staff while shares tank (again) af­ter a new se­ries of set­backs for lead an­tibi­ot­ic

Cem­pra’s Q4 re­view to­day in­cludes a slate of new set­backs, rang­ing from a fail­ure for a Phase III non-in­fe­ri­or­i­ty tri­al of its an­tibi­ot­ic solithromycin in gon­or­rhea to an ear­ly end of an ex­plorato­ry study in NASH as well as a de­ci­sion to shut­ter a tri­al in COPD based on safe­ty con­cerns. And with the fate of its lead pro­gram up in the air, the biotech fol­lowed up with a top-to-bot­tom re­struc­tur­ing, slash­ing most of its pay­roll as it sought to con­serve cash.

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