George Scangos, Vir CEO (BIO via YouTube)

Covid-19 roundup: New preprint sug­gests Omi­cron sub-vari­ant can evade Vir an­ti­body; BioN­Tech-backed non­prof­it un­der­mined WHO eq­ui­ty ef­forts — re­port

Af­ter Omi­cron be­gan spread­ing across the world, it quick­ly be­came clear that Vir-GSK’s an­ti­body sotro­vimab would be the on­ly FDA-ap­proved Covid-19 mon­o­clon­al an­ti­body treat­ment to re­main ef­fec­tive against the new im­mune-eva­sive vari­ant. And it is now the on­ly such treat­ment used in the US, caus­ing mass short­ages.

But a new preprint, re­leased late Wednes­day night by promi­nent Co­lum­bia Uni­ver­si­ty HIV re­searcher and an­ti­body ex­pert David Ho, sug­gests doc­tors may not be able to use sotro­vimab for long. The an­ti­body isn’t ef­fec­tive at neu­tral­iz­ing BA.2, the Omi­cron sub­vari­ant that is gain­ing ground in Eu­rope, the US and much of the globe, the re­searchers found.

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