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Covid-19 roundup: Boehringer pulls a drug out of the pipeline for a PhII Covid-19 tri­al; No­vavax de­lays PhI­II tri­al in US, with PhII da­ta com­ing Fri­day

With big ques­tions still hang­ing over the fate of the vac­cines and drugs now in late-stage de­vel­op­ment for Covid-19, Boehringer In­gel­heim is pulling one of its ear­ly-stage drugs in­to a Phase II tri­al to see if it can help some of the most se­vere­ly af­flict­ed pa­tients.

Put through a safe­ty study last year, re­searchers have been in­trigued by the po­ten­tial of BI 764198 — a TR­PC6 in­hibitor — as a treat­ment for acute res­pi­ra­to­ry dis­tress syn­drome (ARDS), which can cause im­mense dam­age and death for pa­tients ex­posed to the virus.

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Cambridge, MA, USA