Mathai Mammen, Janssen global head of R&D (Rob Tannenbaum, Endpoints News)

Covid-19 roundup: Study shows J&J's shot is much less ef­fec­tive against Delta vari­ant; No­var­tis open to man­u­fac­tur­ing oth­er coro­n­avirus vac­cines — re­port

As the Delta vari­ant rapid­ly spreads across the US — ac­count­ing for 83% of the coun­try’s cas­es, CDC di­rec­tor Rochelle Walen­sky said yes­ter­day — a new study shows the con­cern­ing strain ren­ders John­son & John­son’s sin­gle-dose Covid-19 shot much less ef­fec­tive.

The study, which has not been peer-re­viewed, showed that neu­tral­iz­ing titers in­duced by J&J’s vac­cine de­creased 5.4-fold against the “Delta plus” vari­ant, a mu­ta­tion that sci­en­tists say al­lows the virus to bet­ter at­tack the lungs. In com­par­i­son, titers in­duced by Pfiz­er/BioN­Tech’s can­di­date de­creased by 2.7-fold against the Delta plus vari­ant, and lev­els dropped 3.3-fold for Mod­er­na’s can­di­date.

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