Dana-Farber’s Laurie Glimcher helps launch a NYC biotech upstart with some key insights on immuno-oncology tech
Years before Laurie Glimcher left her job as dean at Weill Cornell Medical College and took the top job at Dana-Farber, the scientist was in the lab probing the way in which certain conditions caused unfolded proteins to clutter endoplasmic reticulum (ER) pathways — studying the ways that played out in the tumor microenvironment.
The ER stress that sparked in turn triggered various survival mechanisms — in particular the tumor-promoting IRE1α pathway — that could help these tumors adapt to a number of threats.
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