Dupix­ent cleared for chron­ic rhi­nos­i­nusi­tis in EU; FDA grants RMAT sta­tus to CARs­gen's CAR-T

Re­gen­eron and Sanofi‘s Dupix­ent — a king in the eczema ther­a­py sec­tor — has cinched its third type 2 in­flam­ma­to­ry dis­ease ap­proval in the EU. On top of se­vere asth­ma and mod­er­ate-to-se­vere atopic der­mati­tis, the drug can now be giv­en to adults who have se­vere chron­ic rhi­nos­i­nusi­tis with nasal poly­po­sis (CR­SwNP). It will be used as an add-on ther­a­py with in­tranasal cor­ti­cos­teroids to treat pa­tients for whom ther­a­py with sys­temic cor­ti­cos­teroids and/or surgery do not pro­vide ad­e­quate dis­ease con­trol.

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