Ea­ger to re­deem its Covid-19 vac­cine, As­traZeneca touts 82.4% ef­fi­ca­cy for 12-week dos­ing sched­ule — but will the FDA buy it?

As­traZeneca and Ox­ford say they now have clin­i­cal ev­i­dence that dos­ing their ade­n­ovirus-based Covid-19 vac­cine 12 weeks apart — a reg­i­men ap­proved by the UK, per­plex­ing many — can ac­tu­al­ly ren­der the shots more ef­fec­tive.

The da­ta will be key to As­traZeneca’s at­tempt to pull it­self back to the up­per ranks of the vac­cine hi­er­ar­chy, where it’s strug­gled as skep­tics poke holes in its ef­fi­ca­cy while pro­duc­tion de­lays trig­ger heat­ed dis­putes with the EU. But it re­mains to be seen what im­pact, if any, the analy­sis will have on the FDA’s think­ing and de­ci­sions re­gard­ing the vac­cine.

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