Dave Ricks, Eli Lilly

Eli Lil­ly bets on an RNA base edit­ing out­fit lever­ag­ing the body's own en­zymes to re­verse mu­ta­tions

With its con­tro­ver­sial Alzheimer’s med do­nanemab near­ly ready for FDA scruti­ny, Eli Lil­ly has grown more em­bold­ened in its ef­forts to be­come the top dog in neu­ro­science. A new part­ner­ship with a qui­et RNA edit­ing play­er fo­cused around neu­ro­science could now add even more bite to Lil­ly’s bark.

Lil­ly will pay $50 mil­lion in up­front cash and eq­ui­ty and up to $1.25 bil­lion in down­stream mile­stones for ac­cess to five RNA edit­ing can­di­dates from Dutch biotech Pro­QR Ther­a­peu­tics, which is us­ing edit­ed oligonu­cleotides to kick off an RNA base edit­ing sys­tem ini­ti­at­ed by the body’s own en­zymes, the part­ners said Wednes­day.

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