EMA sounds its own safety alarm for Pfizer blockbuster, but they’re also not forcing a limit on dosing — yet
The European Medicines Agency has issued a formal warning for patients and physicians to stick with the recommended dose of Xeljanz for treating rheumatoid arthritis and to watch out for potentially lethal blood clots.
Pfizer has been bedeviled by a clear safety signal on their blockbuster JAK inhibitor, flagging the risk of blood clots and death for the twice daily 10 mg dose of Xeljanz, which is authorized at 5 mg twice a day for RA.
Unlock this article instantly by becoming a free subscriber.
You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.