#ESMO16: Boehringer drug flops on OS endpoint; Medivir reorganizes, cuts staff

Fresh on the heels of an embarrassing setback with a lethal cancer drug in-licensed from Hanmi, Boehringer Ingelheim reported over the weekend that nintedanib flunked the co-primary endpoint for overall survival in treating metastatic colorectal cancer. The drug arm did beat out best supportive care for reducing the risk of progression. Boehringer execs say they’re still studying the data, which was reviewed at ESMO.

Exelixis’ drug Cabometyx was in the spotlight at ESMO as well, beating Pfizer’s Sutent as a frontline treatment for metastatic kidney cancer. The drug is already OK’d for second-line use. Shares inched up on the news.

Stockholm-based Medivir is reorganizing, slashing early R&D and administration as it cuts 30 jobs and opts for a special focus on oncology. Medivir will start the process of outsourcing its infectious disease assets.

The best place to read Endpoints News? In your inbox.

Comprehensive daily news report for those who discover, develop, and market drugs. Join 44,700+ biopharma pros who read Endpoints News by email every day.

Free Subscription

Sr. Manager, Regulatory Affairs, CMC
CytomX Therapeutics San Francisco, CA
Marketing Associate - Demand Generation
Catalytic Data Science Charleston, SC
Associate Principal, Life Sciences Partnerships
Flatiron Health New York City or San Francisco

Visit Endpoints Careers ->