Feng Zhang's lab develops potential breakthrough in RNA editing delivery using 'ultracompact' versions of Cas13
As one of the pioneers behind CRISPR, the Broad Institute’s Feng Zhang has fashioned himself into a gene editing Renaissance man in recent years with a finger in every pie. For RNA editing, one of his passion projects, Zhang has worked to crack a chronic delivery logjam — and his team has just made a big breakthrough there.
A team of researchers out of Zhang’s lab has built a pair of “ultracompact” RNA editing tools that can fit inside an adeno-associated virus (AAV) package, potentially creating a breakthrough in the delivery of those gene editing tools into human cells, according to an article published in Nature Biotechnology on Monday.
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