Gala­pa­gos, Ab­b­Vie glimpse ear­ly progress in search of a cys­tic fi­bro­sis triple to ri­val Ver­tex

Ab­b­Vie $AB­BV and its part­ner Gala­pa­gos $GLPG are pleased with some of the ear­ly da­ta they’re see­ing for one piece of their triple drug puz­zle for cys­tic fi­bro­sis. And they’re plan­ning to give Ver­tex a run for its mon­ey on this front.

In a small study in­volv­ing 26 pa­tients with the G551D mu­ta­tion in CFTR, a dose-es­ca­lat­ing reg­i­men of the CFTR po­ten­tia­tor GLPG1837 pro­duced a sta­tis­ti­cal­ly sig­nif­i­cant drop in sweat chlo­ride con­cen­tra­tion.

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