Discovery, R&D

Genentech lines up a new autoimmune R&D alliance on a ‘potentially transformative’ tech

Parvus Therapeutics has just scored a discovery deal with Genentech on autoimmune diseases, putting them in alliance with one of the most sought-after partners in the business.

We don’t know what the upfront is — and typically Genentech isn’t known for splurging big on discovery bets — but the whole deal, biobucks included, weighs in at a prospective $800 million.

James Sabry

Whatever they’re anteing up, Genentech will now hop on the Burlingame, CA-based biotech’s Navacim platform, which converts effector cells into regulatory T cells, Tregs, that in turn whip up immune regulator cells to mob the inflammatory cells that trigger autoimmune diseases like rheumatoid arthritis and multiple sclerosis.

Curtis Ruegg

The aim here is to restore the immune system balance and eradicate the cause of these diseases, which afflict millions. And Parvus is quite proud of its animal data to date. Now they’ll get to take the partnered programs through Phase I, with Genentech taking over at Phase II.

Roche partnering czar James Sabry called it “potentially transformative,” offering a nice endorsement of their new colleagues.

Curtis Ruegg, CEO of Parvus, noted: “Partnering with Genentech will enable Parvus to expand the Navacim pipeline to address several debilitating autoimmune diseases in gastroenterology.”


Image: Paul Sakuma AP


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VP Oncology Biology
Skyhawk Therapeutics Waltham, MA
Associate Director CMC
Elektroki Boston, MA
Director Process Development
Elektroki Boston, MA
Research Scientist - Immunology
Recursion Pharmaceuticals Salt Lake City, UT

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