Gilead offloads a PhII-ready addiction therapy to an upstart which knows this drug well

Eight years ago, Gilead snapped up CV Therapeutics and its angina drug Ranexa for $1.4 billion, looking to beef up its portfolio of cardio drugs. But one of the assets it picked up, an ALDH-2 inhibitor dubbed GS-6637, never made it far in the clinic.

Tested for drug addiction, it cleared Phase I and sat at the bottom of Gilead’s pipeline for liver disease.

Now, though, a group of those ex-CV execs have come back together to create Amygdalla Neurosciences and went back to Gilead to pick up the asset with plans to get into a Phase II study.

“Completion of this transaction launches Amygdala Neurosciences with a Phase-2 ready asset that we believe has the potential to become a treatment for addiction,” said Peter Strumph, Amygdala’s co-founder and CEO. “In 2017, we look forward to initiating clinical trials for the treatment of both cocaine and alcohol use disorders.”

Strumph is working alongside Ivan Diamond, another CV veteran. He told BioCentury that the Gilead was paid in equity and a set of milestones, though he didn’t specify the dollar amounts.

The best place to read Endpoints News? In your inbox.

Comprehensive daily news report for those who discover, develop, and market drugs. Join 44,800+ biopharma pros who read Endpoints News by email every day.

Free Subscription

Sr. Manager, Regulatory Affairs, CMC
CytomX Therapeutics San Francisco, CA
Marketing Associate - Demand Generation
Catalytic Data Science Charleston, SC
Associate Principal, Life Sciences Partnerships
Flatiron Health New York City or San Francisco

Visit Endpoints Careers ->