ICER finds Bio­gen’s new ex­or­bi­tant­ly priced Alzheimer’s drug doesn’t match even an op­ti­mistic view of po­ten­tial clin­i­cal ben­e­fits

Even with a rosy out­look on how Bio­gen’s new Alzheimer’s drug will help those with the de­bil­i­tat­ing and fa­tal dis­ease, the In­sti­tute for Clin­i­cal and Eco­nom­ic Re­view on Wednes­day said the $56,000 an­nu­al price tag “is not in rea­son­able align­ment with its clin­i­cal ben­e­fits.”

In a new analy­sis, ICER said ad­u­canum­ab would re­quire an 85%-95% dis­count from the list price in or­der to be cost ef­fec­tive. Due to Bio­gen’s con­flict­ing da­ta and the “very small es­ti­mat­ed im­pact” of ad­u­canum­ab on the pro­gres­sion of mod­er­ate and se­vere Alzheimer’s dis­ease, the watch­dog said a fair price would be be­tween $3,000 per year— if the drug is not as ef­fec­tive as promised —to $8,400, if it is.

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