In an up­date, Gilead spot­lights top-line hits amid a mixed set of PhII da­ta for its $600M NASH drug

Six months af­ter putting out some stel­lar ear­ly-stage da­ta from a study of its NASH drug GS-0976, Gilead has come back with the full slate of re­sults, un­der­scor­ing the po­ten­tial here as well as the chal­lenge ahead for re­searchers.

In the break­down, in­ves­ti­ga­tors point­ed to a dose-de­pen­dent re­sponse on two key mea­sures of the dis­ease, re­peat­ing a 43% re­duc­tion in liv­er fat among a small group of pa­tients tak­ing the high dose of the drug, in-li­censed from Nim­bus for a jaw-drop­ping $600 mil­lion in quick cash.

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