Io­vance picks up IL-2 Pro­leukin for $200M+ up­front; Es­trel­la Bio­phar­ma to wait for SPAC deal fin­ish

The UK-based biotech Clin­i­gen will di­vest from one of its IL-2 can­di­dates and sell it to Io­vance Bio­ther­a­peu­tics.

In an an­nounce­ment on Mon­day, Io­vance will pay £166.7 ($205.9 mil­lion) to Clin­i­gen for Pro­leukin, a cy­tokine that can be used in treat­ing metasta­t­ic re­nal cell car­ci­no­ma and metasta­t­ic melanoma but has been in­ves­ti­gat­ed for oth­er us­es as well. The agree­ment will al­so see a £41.7 mil­lion ($51.4 mil­lion) mile­stone pay­ment up­on the “first ap­proval” of li­fileu­cel for ad­vanced melanoma. The deal is ex­pect­ed to close in the first quar­ter of 2023.

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