Iovance's TIL therapy makes early headway in lung cancer; Antios and Arbutus join hands on HBV combo treatment
Iovance has posted a first look at its tumor infiltrating lymphocytes as a treatment for non-small cell lung cancer, paving the way for a pivotal study.
Among 28 patients enrolled in Cohort 3B of the IOV-COM-202 basket study — 24 of whom were evaluable — investigators recorded an overall response rate of 21.4% at the interim, with 1 complete response and 5 partial responses. All patients in the group had progressed on prior immune checkpoint inhibitor therapy, and some had received tyrosine kinase inhibitors. The six responders also underwent chemotherapy.
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