Peter Smith (file photo)

Is there room for a new way to drug RNA? ARCH, Fore­site join At­las, The Col­umn Group for $81M bet

By now, it ap­pears that drug hunters have ex­ploit­ed just about every ther­a­peu­tic an­gle hav­ing to do with RNA. Lever­ag­ing RNA as a ther­a­py? Check. Mak­ing an­ti­sense oligonu­cleotides that in­duce a par­tic­u­lar change? Check. Find­ing small mol­e­cules that bind to RNA, tar­get­ing the en­zymes that mod­i­fy it, or even cre­at­ing a way to ed­it it let­ter by let­ter? Check, check, check. But At­las and The Col­umn Group — both ac­tive in­vestors of those ef­forts — saw yet an­oth­er ap­proach to be tried.

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