Jazz gam­bles $175M on a triple-pronged armed an­ti­body pact with Im­muno­Gen

Jazz Phar­ma­ceu­ti­cals is team­ing up with Im­muno­Gen on a slate of armed an­ti­bod­ies.

Jazz $JAZZ will pay $175 mil­lion — $75 mil­lion up­front and $100 mil­lion in re­search sup­port — to claim opt-in rights on a line­up of three an­ti­body-drug con­ju­gates ei­ther just in the clin­ic or planned for hu­man stud­ies. At the top of the list is Im­muno­Gen’s $IMGN Phase I ADC IMGN779, a CD33-tar­get­ed ADC for the treat­ment of acute myeloid leukemia, and IMGN632, a CD123-tar­get­ed ADC for hema­to­log­i­cal ma­lig­nan­cies be­ing teed up for its first Phase I. An­oth­er pro­gram will be des­ig­nat­ed for the col­lab­o­ra­tion lat­er.

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