J&J beefs up neu­ro pipeline, bags a new de­pres­sion drug from Cere­cor in $45M deal

Eight months af­ter CERC-501 failed in a key mid-stage study for treat­ing nico­tine with­draw­al, Cere­core has out­li­censed the drug rights on de­pres­sion to phar­ma gi­ant J&J for $25 mil­lion in cash plus an­oth­er $20 mil­lion mile­stone.

The drug, an oral kap­pa opi­oid re­cep­tor an­tag­o­nist, has been stud­ied for ma­jor de­pres­sion as well as sub­stance abuse at the mi­cro­cap. And it will now join a neu­ro­sciences pipeline at J&J that in­cludes a late-stage pro­gram for an in­haled ver­sion of ke­t­a­mine, a horse tran­quil­iz­er that has demon­strat­ed dra­mat­ic re­spons­es for quick­ly lift­ing de­pres­sion and sui­ci­dal think­ing — and which al­so has ma­jor psy­chotrop­ic side ef­fects.

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