J&J hands Ar­row­head a plum $3.7B deal for hep B-plus 3 — cor­ralling a pos­si­ble game-chang­ing RNAi drug

Two years af­ter Ar­row­head Phar­ma­ceu­ti­cals $AR­WR con­ced­ed that a sub­stan­tial seg­ment of their RNAi pipeline was hope­less­ly com­pro­mised and had to be jet­ti­soned, crip­pling their stock price, the biotech is stag­ing a ma­jor come­back.

In the wake of an ear­ly look at pos­i­tive ear­ly re­turns for their he­pati­tis B can­di­date, J&J is step­ping up with one of their fa­mous li­cens­ing pacts, fork­ing over $250 mil­lion in cash for an up­front and eq­ui­ty stake, sea­son­ing it with a $50 mil­lion near-term plum and promis­ing much, much more for a break­through per­for­mance in a key dis­ease tar­get.

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